Background: MRP4 is an endogenous transporter of cyclic nucleotides that can regulate cell migration. The role of MRP4 in fibroblast migration is unknown.

Background: ITK-SYK is an oncogenic fusion protein in patients with peripheral T cell lymphomas carrying a unique translocation.

Background: ER stress impairs progression through G1 and G2 phases of the cell cycle.

Background: Beta cell VEGF-A is critical for islet vascularization and Insulin secretion.

Background: Soluble melanoma cell adhesion molecule (sMCAM/sCD146) promotes angiogenic effects on endothelial progenitor cells (EPC).

Background: Somatic cell reprogramming is an inefficient process because of the existence of roadblocks.

Background: Intestinal epithelial wound closure requires dynamic regulation/turnover of cell-matrix adhesions.

Background: The mechanism by which KCa3.1 regulates cell proliferation remains elusive.

Background: Cyclin/CDKs play an important role in cell cycle regulation.

Background: Glioblastoma is characterized by heightened cell invasion and therapeutic resistance.

Background: The licensing inhibitor geminin must be regulated to ensure once per cell cycle replication.

Background: The PCP pathway controls many cell processes during development.

Background: Signaling mechanisms regulating rat embryonic stem cell (rESC) pluripotency are understood poorly.

Background: A limited number of cargoes specific for importin-β family nucleocytoplasmic transport carriers have been reported. We have developed a stable isotope labeling by amino acids in cell culture (SILAC)-based transport method to identify specific cargo.

Background: MiR-302 regulates pluripotency genes and helps somatic cell reprogramming.

Background: Cyclin D1/Cdk4 and NDR1/2 are critical kinases in cell cycle regulation.

Background: The E3 ubiquitin ligase ASB2α triggers proteasomal degradation of filamins and regulates cell spreading and differentiation.

Background: Growth factors induce actin cytoskeletal reorganization and cell migration in fibroblast cells.

Background: Activated TRAIL receptors accumulate in lipid raft membrane domains to trigger cell death.

Background: Kinase activity of ROCK II, an important regulator of cell migration, is controlled by its endogenous inhibitor CRMP-2.