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‣ Survival of Dental Implants in the Cleft Area-A Retrospective Study

FERREIRA JR., Samuel de Barros; ESPER, Luis Augusto; SBRANA, Michyele Cristhiane; RIBEIRO, Ingrid Webb Josephson; ALMEIDA, Ana Lucia Pompeia Fraga de
Fonte: ALLIANCE COMMUNICATIONS GROUP DIVISION ALLEN PRESS Publicador: ALLIANCE COMMUNICATIONS GROUP DIVISION ALLEN PRESS
Tipo: Artigo de Revista Científica
Português
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Objective To evaluate the survival rate of dental implants placed in the cleft area Design Retrospective study Setting Hospital for Rehabilitation of Craniofacial Anomalies, Brazil Institutional Tertiary Healthcare Center Patients 120 patients who received dental implants in the grafted cleft area in the years 1999 to 2005 Interventions Clinical data were evaluated from the records of 120 patients according to the following criteria placement grafted, cleft area, and age at surgery, age at placement of dental implants, site and dimension of implants, interval between placement of implants and the last clinical follow-up, and interval between placement and removal or indication for removal of implants Main Outcome Measures Percentage of survival rate of implants Results Mean age at placement of the bone graft was 17 6 years and 21 years at placement of implants A total of 123 cleft areas received secondary bone graft and bone graft to install implants (regraft) The mean survival rate was 34 months since placement of the implant to the last clinical follow-up and 26 months since placement of the prosthesis Seven dental implants were removed The survival rate since placement to the last clinical follow-up was 94 3% Conclusion Rehabilitation of the cleft area with dental implants is a viable and secure alternative...

‣ The Prospective and Retrospective Memory Questionnaire: A population-based random sampling study

PIAUILINO, D. C.; BUENO, O. F. A.; TUFIK, S.; BITTENCOURT, L. R.; SANTOS-SILVA, R.; HACHUL, H.; GORENSTEIN, C.; POMPEIA, S.
Fonte: PSYCHOLOGY PRESS Publicador: PSYCHOLOGY PRESS
Tipo: Artigo de Revista Científica
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The Prospective and Retrospective Memory Questionnaire (PRMQ) has been shown to have acceptable reliability and factorial, predictive, and concurrent validity. However, the PRMQ has never been administered to a probability sample survey representative of all ages in adulthood, nor have previous studies controlled for factors that are known to influence metamemory, such as affective status. Here, the PRMQ was applied in a survey adopting a probabilistic three-stage cluster sample representative of the population of Sao Paulo, Brazil, according to gender, age (20-80 years), and economic status (n=1042). After excluding participants who had conditions that impair memory (depression, anxiety, used psychotropics, and/or had neurological/psychiatric disorders), in the remaining 664 individuals we (a) used confirmatory factor analyses to test competing models of the latent structure of the PRMQ, and (b) studied effects of gender, age, schooling, and economic status on prospective and retrospective memory complaints. The model with the best fit confirmed the same tripartite structure (general memory factor and two orthogonal prospective and retrospective memory factors) previously reported. Women complained more of general memory slips, especially those in the first 5 years after menopause...

‣ Evisceração : análise de 126 procedimentos realizados no setor de plástica ocular do Hospital Banco de Olhos de Porto Alegre entre 1988 e 2002; Evisceration : retrospective analysis of the 126 files from the Setor de Plástica Ocular do Hospital Banco de Olhos de Porto Alegre - Brazil from 1988 to 2002

Lovato, Fernanda Verçosa; Tonietto, Ana Paula; Mason, Eduardo Marques; Fortes Filho, João Borges
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
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Objetivo: Levantar os aspectos clínicos, a faixa etária e o sexo de todos os pacientes submetidos a procedimento cirúrgico de evisceração que foram atendidos no setor de plástica ocular do Hospital Banco de Olhos de Porto Alegre, no período entre 1988 até 2002. Métodos: Estudo de prevalência retrospectivo com revisão de prontuários dos pacientes submetidos à evisceração no período citado para determinar a doença primária que gerou a indicação cirúrgica, bem como a faixa etária e o sexo neste grupo de pacientes. Resultados: Entre os 126 casos estudados, 42,85% dos pacientes foram eviscerados devido a um trauma prévio (trauma = causa mais freqüente), 22,22% dos casos foram eviscerados por phithisis bulbi que foi a segunda causa mais comum encontrada. Outras causas menos freqüentes de evisceração foram úlceras de córnea e microftalmia. Os pacientes com maior média de idade foram os que tinham glaucoma neovascular e os mais jovens os que tinham microftalmia. Conclusão: A causa mais freqüente de indicação de evisceração no setor de plástica ocular do Hospital Banco de Olhos de Porto Alegre foi o trauma, que acometeu preferencialmente homens com média de idade de 30 anos, ao contrário do encontrado na literatura. Em segundo lugar os pacientes que chegaram ao serviço com olhos atróficos...

‣ Dental trauma involving root fracture and periodontal ligament injury: A 10-year retrospective study

Panzarini, Sônia Regina; Pedrini, Denise; Poi, Wilson Roberto; Sonoda, Celso Koogi; Brandini, Daniela Atili; de Castro, José Carlos Monteiro
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 229-234
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The purpose of this retrospective study was to analyze the cases of traumatic dental injuries involving root fracture and/or periodontal ligament injury (except avulsion) treated at the Discipline of Integrated Clinic, School of Dentistry of Araçatuba, São Paulo State University (UNESP), Brazil, from January 1992 to December 2002. Clinical and radiographic records from 161 patients with 287 traumatized teeth that had sustained root fracture and/or injuries to the periodontal ligament were examined. The results of this survey revealed that subluxation (25.09%) was the most common type of periodontal ligament injury, followed by extrusive luxation (19.86%). There was a predominance of young male patients and most of them did not present systemic alterations. Among the etiologic factors, the most frequent causes were falls and bicycle accidents. Injuries on extraoral soft tissues were mostly laceration and abrasion, while gingival and lip mucosa lacerations prevailed on intraoral soft tissues injuries. Radiographically, the most common finding was an increase of the periodontal ligament space. The most commonly performed treatment was root canal therapy. Within the limits of this study, it can be concluded that traumatic dental injuries occur more frequently in young male individuals...

‣ MicroRNA expression as risk biomarker of breast cancer metastasis : a pilot retrospective case-cohort study

Marino, Augusto L. F.; Evangelista, Adriane F.; Vieira, René A. C.; Macedo, Taciane; Kerr, Ligia M.; Machado, Lucas Faria Abrahão; Longatto Filho, Adhemar; Silveira, Henrique C. S.; Marques, Marcia M. C.
Fonte: Springer Publicador: Springer
Tipo: Artigo de Revista Científica
Publicado em /12/2014 Português
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Background: MicroRNAs (miRNAs) are small, non-coding RNA molecules involved in post-transcriptional gene regulation and have recently been shown to play a role in cancer metastasis. In solid tumors, especially breast cancer, alterations in miRNA expression contribute to cancer pathogenesis, including metastasis. Considering the emerging role of miRNAs in metastasis, the identification of predictive markers is necessary to further the understanding of stage-specific breast cancer development. This is a retrospective analysis that aimed to identify molecular biomarkers related to distant breast cancer metastasis development. Methods: A retrospective case cohort study was performed in 64 breast cancer patients treated during the period from 1998-2001. The case group (n = 29) consisted of patients with a poor prognosis who presented with breast cancer recurrence or metastasis during follow up. The control group (n = 35) consisted of patients with a good prognosis who did not develop breast cancer recurrence or metastasis. These patient groups were stratified according to TNM clinical stage (CS) I, II and III, and the main clinical features of the patients were homogeneous. MicroRNA profiling was performed and biomarkers related to metastatic were identified independent of clinical stage. Finally...

‣ Prophylactic Use of Liposomal Amphotericin B in Preventing Fungal Infections Early After Liver Transplantation: a Retrospective, Single-Center Study

Antunes, AM; Teixeira, C; Corvo, ML; Perdigoto, R; Barroso, E; Marcelino, P
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em //2014 Português
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In this study the authors evaluated the efficacy of prophylaxis with liposomal amphotericin B (L-AmB) in the incidence of fungal infections (FI) during the first 3 months after liver transplant (LT). The study was retrospective and accessed a 4-year period from 2008 to 2011. All patients who died in the first 48 hours after LT were excluded. Patients were divided by the risk groups for FI: Group 1, high-risk (at least 1 of the following conditions: urgent LT; serum creatinine >2 mg/dL; early acute kidney injury [AKI] after LT; retransplantation; surgical exploration early post-LT; transfused cellular blood components [>40 U]); and Group 2, low-risk patients. Group 1 patients were further separated into those who received antifungal prophylaxis with L-AmB and those who did not. Prophylaxis with L-AmB consisted of intravenous administration of L-AmB, 100 mg daily for 14 days. Four hundred ninety-two patients underwent LT; 31 died in the first 48 hours after LT. From the remaining 461 patients, 104 presented with high-risk factors for FI (Group 1); of these, 66 patients received antifungal prophylaxis and 38 did not. In this group 8 FI were observed, 5 in patients without antifungal prophylaxis (P = .011). Three more FI were identified in Group 2. By logistic regression analysis...

‣ Prophylactic Use of Liposomal Amphotericin B in Preventing Fungal Infections Early After Liver Transplantation: a Retrospective, Single-Center Study

Antunes, AM; Teixeira, C; Corvo, ML; Perdigoto, R; Barroso, E; Marcelino, P
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em //2014 Português
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In this study the authors evaluated the efficacy of prophylaxis with liposomal amphotericin B (L-AmB) in the incidence of fungal infections (FI) during the first 3 months after liver transplant (LT). The study was retrospective and accessed a 4-year period from 2008 to 2011. All patients who died in the first 48 hours after LT were excluded. Patients were divided by the risk groups for FI: Group 1, high-risk (at least 1 of the following conditions: urgent LT; serum creatinine >2 mg/dL; early acute kidney injury [AKI] after LT; retransplantation; surgical exploration early post-LT; transfused cellular blood components [>40 U]); and Group 2, low-risk patients. Group 1 patients were further separated into those who received antifungal prophylaxis with L-AmB and those who did not. Prophylaxis with L-AmB consisted of intravenous administration of L-AmB, 100 mg daily for 14 days. Four hundred ninety-two patients underwent LT; 31 died in the first 48 hours after LT. From the remaining 461 patients, 104 presented with high-risk factors for FI (Group 1); of these, 66 patients received antifungal prophylaxis and 38 did not. In this group 8 FI were observed, 5 in patients without antifungal prophylaxis (P = .011). Three more FI were identified in Group 2. By logistic regression analysis...

‣ Retrospective Study on Dengue in Fortaleza, State of Ceará, Brazil

Cunha,RV da; Miagostovich,MP; Petrola,Z; Araújo,ESM de; Cortez,D; Pombo,V; Souza,RV de; Nogueira,RMR; Schatzmayr,HG
Fonte: Instituto Oswaldo Cruz, Ministério da Saúde Publicador: Instituto Oswaldo Cruz, Ministério da Saúde
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/1998 Português
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A retrospective serologic study was carried out in Fortaleza, State of Ceará, Brazil, in order to detect the dengue virus activity before recognizing the epidemic of 1994. Mac-Elisa was performed by using a mixture of specific DEN-1 and DEN-2 antigens on serum samples from the Emilio Ribas Laboratory collection. Samples were obtained from 1,224 patients with exanthematic febrile disease and negative serological results for rubella. All specimens were taken during November 1993 to May 1994. The results confirmed dengue infections in Fortaleza by November 1993, approximately six months before the beginning of the epidemic, proving how misleading diagnosis of dengue infection are still troublesome, in spite of the strong dengue activity in Ceará. The authors stress the urgent necessity to implement the active surveillance system in order to prevent another extensive dengue fever epidemics in the state. Epidemiological background of the dengue activity in the State of Ceará is also described.

‣ Demodex Dermatitis: A Retrospective Analysis of Clinical Diagnosis and Successful Treatment with Topical Crotamiton

Bikowski, Joseph B.; Del Rosso, James Q.
Fonte: Matrix Medical Communications Publicador: Matrix Medical Communications
Tipo: Artigo de Revista Científica
Publicado em /01/2009 Português
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Given the reported common occurrence of Demodex dermatitis in the general population, Demodex dermatitis—considered as a separate condition from rosacea and seborrheic dermatitis—was evaluated in a retrospective case analysis.

‣ Time lapse from the occurrence of trauma to the definitive management of mandibular fractures: a retrospective study

Mahajan, S. V.; Datarkar, A. N.; Borle, R. M.
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
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The surgical management of maxillofacial trauma has come a long way in the last four millennia and without doubt will go further. The principles are not new but the interpretation constantly changes. A retrospective review of 52 inpatient records of mandibular fracture patients was done for the period 1 January 2003 to 30 June 2005.

‣ Clinical Efficacy of Short Contact Topical 5-Fluorouracil in the Treatment of Keratoacanthomas: A Retrospective Analysis

Thompson, Bobbye J.; Ravits, Margaret; Silvers, David N.
Fonte: Matrix Medical Communications Publicador: Matrix Medical Communications
Tipo: Artigo de Revista Científica
Publicado em /11/2014 Português
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Objective: To determine the efficacy of treating patients with a recent onset, biopsy-proven keratoacanthoma with short-contact topical 5% 5-fluorouracil cream twice daily until resolution. Design: Chart review of 10 patients who applied 5% 5-fluorouracil for the treatment of biopsy-proven keratoacanthoma. Setting: Outpatient clinic of a board-certified dermatologist. Participants: The study population was 90-percent women (9/10), 10-percent men (1/10) and ranged in ages from 52 to 92 years old with a mean age of 74.4. Measurements: Patients were followed for weekly visits for the duration of their treatment and at varying, less-frequent intervals after resolution of the lesion clinically. Photographs were taken at each visit. Results: The authors performed a retrospective analysis of 10 patients with biopsy-confirmed keratoacanthomas treated with topical 5-fluorouracil. One patient elected to have Mohs surgery after one week of topical 5-fluorouracil due to personal concern and cosmetic appearance and did not complain of any side effects due to the drug. Of the nine patients that remained on topical 5-fluorouracil, all patients had complete resolution of the lesion within six weeks. The range in the number of weeks to resolution was four to six weeks. Two patients required a one- to two-week drug holiday secondary to erythema...

‣ Dermatological Adverse Events Associated with Topical Brimonidine Gel 0.33% in Subjects with Erythema of Rosacea: A Retrospective Review of Clinical Studies

Holmes, Anna D.; Waite, Kimberly A.; Chen, Michael C.; Palaniswamy, Kiruthi; Wiser, Thomas H.; Draelos, Zoe D.; Rafal, Elyse S.; Werschler, W. Philip; Harvey, Alison E.
Fonte: Matrix Medical Communications Publicador: Matrix Medical Communications
Tipo: Artigo de Revista Científica
Publicado em /08/2015 Português
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Background: The topical α2 adrenergic receptor agonist brimonidine gel 0.33% is an effective and safe pharmacological treatment for the facial erythema of rosacea. However, adverse events of worsened redness have occasionally been reported with its use. Objective: A detailed analysis of adverse events is needed to accurately define worsening erythema and the adverse-events profile associated with brimonidine gel treatment. Methods and measurements: A retrospective review of related dermatological adverse events occurring in subjects enrolled in the two pivotal four-week Phase 3 studies and the 52-week long-term safety study for brimonidine gel was conducted. Measurements included total adverse-event incidences; number of subjects experiencing adverse events; study discontinuation due to adverse events, severity, onset, episodic duration period; and correlation of adverse events to subject disposition, and rosacea profile. Results: Flushing and erythema were the most commonly reported adverse events, occurring in a total of 5.4 percent of subjects in the Phase 3 studies and in 15.4 percent in the long-term study. Most adverse events were mild or moderate in severity, transient, and intermittent. Adverse events occurred early in treatment...

‣ Chronic periodontitis and its possible association with oral squamous cell carcinoma – a retrospective case control study

Moergel, Maximilian; Kämmerer, Peer; Kasaj, Adrian; Armouti, Evangelia; Alshihri, Abdulmonem; Weyer, Veronika; Al-Nawas, Bilal
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Artigo de Revista Científica
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Introduction: Different inflammatory processes may trigger the development of malignancies. Therefore, the aim of the present study was to evaluate a potential association between radiological determined chronic periodontitis (CPA) and oral squamous cell carcinoma (OSCC). Methods: In a retrospective study, OSCC-patients and a control group without malignant tumors were radiographically examined for bone loss. Via telephone survey and questionnaire, general clinical data on the individual oral hygiene and concomitant diseases together with tobacco and alcohol use were assessed and data were compared between the groups. Results: 178 OSCC-patients and 123 controls were included. In univariate analysis, a statistically relevant higher mean bone loss was seen in the OSCC group (4.3 mm (SD: 1.8; 95% confidence interval (CI): 4-4.6) vs. 2.9 mm (SD: 0.7; 95% CI: 2.8-3); p < 0.001)). This was confirmed in a multivariate regression model (OR: 2.4, 95% CI: 1.5-3.8; p < 0.001). A history of periodontal treatment was associated with significantly reduced OSCC risk (p < 0.001; OR: 0.2, CI: 0.1-0.5). Conclusions: CPA is a common disease and the monitoring as well as the treatment of such a chronic oral inflammation may be beneficial in reducing one potential cause of OSCC. Therefore...

‣ Traumatismo alveolodent??rio na denti????o dec??dua: associa????o do grau de maturidade radicular no momento de injuria e sequelas ap??s acompanhamento longitudinal retrospectivo.; Alveolodent??rio trauma in primary dentition: association of the degree of maturity at the time of root injury and sequelae after longitudinal retrospective

SHQAIR, Ayah Qassem Ahmad
Fonte: Universidade Federal de Pelotas; Odontologia; Programa de P??s-Gradua????o em Odontologia; UFPel; BR Publicador: Universidade Federal de Pelotas; Odontologia; Programa de P??s-Gradua????o em Odontologia; UFPel; BR
Tipo: Dissertação Formato: application/pdf
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This study aimed at investigating the influence of the radicular maturity level of primary teeth in the sequelae of dental trauma as well as the moment that such sequelae take place. Two longitudinal retrospective studies, which collected data from dental records and radiographies of patients with dental trauma in one or both upper central primary incisors. was conducted. In the first one, sequelae such as crown discoloration, pulp canal obliteration and inflammatory root resorption were evaluated in a follow-up period 12-18 months after the trauma, using the registers from 150 patients. In the second study, only intruded and subluxated teeth were included. Clinical and radiographic sequelae such as crown discoloration, fistula, pulp canal obliteration, inflammatory and internal root resorption were evaluated. The data regarding the sequelae were distributed into eight follow-up intervals: 0-30 days; 31-90 days; 91-180 days; 181-365 days; 1 to 2 years; 2 to 3 years; 3 to 4 years and > 4 years. From 150 patients included at the first study, 118 (78.7%) presented luxations and 32 (21.3%) had dental fractures. Shortly after the injury, 13 teeth (9.2%) presented immature roots, 114 (80.3%) presented closed apexes, and 15 of them (10.6%) had visible root resorption. The results showed an association between the radicular maturity level of traumatized teeth and the occurrence pulp obliteration (P = 0.023) and inflammatory root resorption (P = 0.004) after 12-18 months of follow-up period. There was also an association between the type of injury and the occurrence of crown discoloration (P = 0.036) as well as the type of injury and the development of pulp canal obliteration (P = 0.001). Regarding the second study...

‣ Hypersensitivity reactions to human papillomavirus vaccine in Australian schoolgirls: retrospective cohort study

Kang, L.; Crawford, N.; Tang, M.; Buttery, J.; Royle, J.; Gold, M.; Ziegler, C.; Quinn, P.; Elia, S.; Choo, S.
Fonte: British Med Journal Publ Group Publicador: British Med Journal Publ Group
Tipo: Artigo de Revista Científica
Publicado em //2008 Português
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OBJECTIVE: To describe the outcomes of clinical evaluation, skin testing, and vaccine challenge in adolescent schoolgirls with suspected hypersensitivity to the quadrivalent human papillomavirus vaccine introduced in Australian schools in 2007. DESIGN: Retrospective cohort study. SETTING: Two tertiary paediatric allergy centres in Victoria and South Australia, Australia. PARTICIPANTS: 35 schoolgirls aged 12 to 18.9 years with suspected hypersensitivity reactions to the quadrivalent human papillomavirus vaccine. MAIN OUTCOME MEASURES: Clinical review and skin prick and intradermal testing with the quadrivalent vaccine and subsequent challenge with the vaccine. RESULTS: 35 schoolgirls with suspected hypersensitivity to the quadrivalent human papillomavirus vaccine were notified to the specialised immunisation services in 2007, after more than 380 000 doses had been administered in schools. Of these 35 schoolgirls, 25 agreed to further evaluation. Twenty three (92%) experienced reactions after the first dose. Thirteen (52%) experienced urticaria or angio-oedema, and of these, two experienced anaphylaxis. Thirteen had generalised rash, one with angio-oedema. The median time to reaction was 90 minutes. Nineteen (76%) underwent skin testing with the quadrivalent vaccine: all were skin prick test negative and one was intradermal test positive. Eighteen (72%) were subsequently challenged with the quadrivalent vaccine and three (12%) elected to receive the bivalent vaccine. Seventeen tolerated the challenge and one reported limited urticaria four hours after the vaccine had been administered. Only three of the 25 schoolgirls were found to have probable hypersensitivity to the quadrivalent vaccine. CONCLUSION: True hypersensitivity to the quadrivalent human papillomavirus vaccine in Australian schoolgirls was uncommon and most tolerated subsequent doses.; Liew Woei Kang...

‣ Effect of reduced immunosuppression after kidney transplant failure on risk of cancer: population based retrospective cohort study

van Leeuwen, M.; Webster, A.; McCredie, M.; Stewart, J.; McDonald, S.; Amin, J.; Kaldor, J.; Chapman, J.; Vajdic, C.; Grulich, A.
Fonte: British Med Journal Publ Group Publicador: British Med Journal Publ Group
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
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Objective: To compare cancer incidence in kidney transplant recipients during periods of transplant function (and immunosuppression) and after transplant failure (when immunosuppression is ceased or reduced). Design, setting, and participants: Nationwide, population based retrospective cohort study of 8173 Australian kidney transplant recipients registered on the Australia and New Zealand Dialysis and Transplant Registry who first received a transplant during 1982-2003. Incident cancers were ascertained using linkage with national cancer registry records. Main outcome measures: Cancer-specific standardised incidence ratios for periods of transplant function and for dialysis after transplant failure. Incidence was compared between periods using multivariate incidence rate ratios adjusted for current age, sex, and duration of transplantation. Results: All cases of Kaposi’s sarcoma occurred during transplant function. Standardised incidence ratios were significantly elevated during transplant function, but not during dialysis after transplant failure, for non-Hodgkin’s lymphoma, lip cancer, and melanoma. For each of these cancers, incidence was significantly lower during dialysis after transplant failure in multivariate analysis (incidence rate ratios 0.20 (95% CI 0.06 to 0.65) for non-Hodgkin’s lymphoma...

‣ Effects of vaccination on onset and outcome of Dravet syndrome: a retrospective study

McIntosh, A.; McMahon, J.; Dibbens, L.; Iona, X.; Mulley, J.; Scheffer, I.; Berkovic, S.
Fonte: Lancet Ltd Publicador: Lancet Ltd
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
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BACKGROUND: Pertussis vaccination has been alleged to cause an encephalopathy that involves seizures and subsequent intellectual disability. In a previous retrospective study, 11 of 14 patients with so-called vaccine encephalopathy had Dravet syndrome that was associated with de-novo mutations of the sodium channel gene SCN1A. In this study, we aimed to establish whether the apparent association of Dravet syndrome with vaccination was caused by recall bias and, if not, whether vaccination affected the onset or outcome of the disorder. METHODS: We retrospectively studied patients with Dravet syndrome who had mutations in SCN1A, whose first seizure was a convulsion, and for whom validated source data were available. We analysed medical and vaccination records to investigate whether there was an association between vaccination and onset of seizures in these patients. Patients were separated into two groups according to whether seizure onset occurred shortly after vaccination (vaccination-proximate group) or not (vaccination-distant group). We compared clinical features, intellectual outcome, and type of SCN1A mutation between the groups. FINDINGS: Dates of vaccination and seizure onset were available from source records for 40 patients. We identified a peak in the number of patients who had seizure onset within 2 days after vaccination. Thus...

‣ Implementation of a hospital oral care protocol and recording of oral mucositis in children receiving cancer treatment: a retrospective and a prospective study

Qutob, A.; Allen, G.; Gue, S.; Revesz, T.; Logan, R.; Keefe, D.
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
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PURPOSE: This retrospective/prospective study was carried out to implement a standardized hospital oral care protocol and record the incidence of oral mucositis for inpatients with childhood cancer. METHODS: The implementation process included stages of collaboration, consultation, education, and evaluation. The retrospective part of the study documented the existing hospital oral care protocol and audited medical records of all pediatric patients diagnosed with cancer over a 12-month period. The frequency of recorded oral mucositis and the rate of referral to the pediatric dentistry department were assessed. Following evaluation of the retrospective study, the literature was searched to create a new hospital oral care protocol. Referral to the dental department was standardized and frequent in-service presentations were given to staff. The oral mucositis scale was recorded daily for all inpatients, and compliance rates were assessed. RESULTS: Fifty-nine patients’ medical records were audited during the retrospective study. Oral mucositis prevalence was clearly documented at 34%, while an additional 20% lacked a definitive diagnosis. During the prospective study, 38 patients were followed and had a verified incidence of oral mucositis of 33%. The rate of compliance of implementing the oral mucositis scale improved from 41% during the first 4 months to 87% during last 3 months. Referral rates to the dental department increased from 53% during the retrospective study to 100% during the prospective study. CONCLUSIONS: Mutual understanding and collaboration between the oncology and dental departments in hospitals is crucial for standardizing patient care and for improving oral care standards.; Akram F. Qutob...

‣ Clinical pathway management of total knee arthroplasty: a retrospective comparative study

Pearson, S.; Moraw, I.; Maddern, G.
Fonte: Blackwell Science Asia Publicador: Blackwell Science Asia
Tipo: Artigo de Revista Científica
Publicado em //2000 Português
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BACKGROUND: Clinical pathways facilitate the management of defined patient groups using interdisciplinary plans of care. The aim of the present study was to evaluate the effectiveness of a clinical pathway in improving a range of selected outcome measures in patients who have undergone total knee arthroplasty (TKA). METHODS: The present study was conducted at Queen Elizabeth Hospital, Adelaide. Using a retrospective comparative study design, 119 TKA patients who were managed on a clinical pathway from July 1997 to January 1998 (group 2) were compared with a retrospective group of 58 patients who underwent the same procedure from July 1996 to January 1997 (group 1) prior to the pathway's implementation. The following outcomes were measured: length of hospital stay; postoperative complications; readmissions and emergency service visits within 6 months of discharge; day of transfer to the convalescent unit; convalescent unit utilization and admission and discharge times. RESULTS: There was a significant reduction in the median length of stay in group 2 patients (9 vs 7 days; P < 0.0001). In addition there was a 66% increase in the proportion of patients in group 2 who were admitted on the day of surgery (P < 0.0001) and a 19.6% increase in the number of patients discharged within 8 postoperative days (P < 0.01). There were no significant differences between the groups with respect to the occurrence of postoperative complications. Although there was a trend toward a reduction in emergency service utilization and readmissions within 6 months of discharge for patients managed on the pathway...

‣ Retrospective labelling in premise-conclusion metatext: An English-Spanish contrastive study of research articles on business and economics

Moreno, Ana I.
Fonte: Elsevier Publicador: Elsevier
Tipo: Artículo Formato: 125365 bytes; application/pdf
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19 pages, 5 tables.-- Printed version published Oct 2004.; The present study assumes that, despite the relative uniformity of research articles (RAs) imposed by the requirements of the genre, there may be intercultural variation in the rhetorical preferences of different writing cultures. The paper develops further Moreno’s (1998) model for the comparison of the metatext employed in English and Spanish to signal premise-conclusion intersentential coherence relations. It does so by focusing on the types and preference of use of retrospective cohesive mechanisms employed in premise-conclusion metatext to label the premise from which the upcoming conclusion is to be drawn. Variability is searched for in different aspects of the label arriving at the following conclusions: 1) As regards the extent to which authors make explicit reference to the stretch of discourse from which the upcoming conclusion is to be drawn, Spanish academics show a greater tendency towards the use of fuzzy labels; 2) The overall distribution of the lexical range of labels is also different, English showing a greater tendency towards the use of non-metalinguistic labels. Retrospective labels have a greater tendency to add interpersonal meanings in English both 3) through the label itself and 4) through its modification; 5) The various ways in which modifiers in retrospective labels add ideational meaning seem to be distributed differently.; The present study is part of a research project financed by the Spanish Ministry of Science and Technology—Plan Nacional de I+D+I (2000–2003) Ref: BFF2001-0112-...